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Trimethobenzamide hydrochloride
CAS No. 554-92-7
Trimethobenzamide hydrochloride( Ro 2-9578 | Tribenzagan Hydrochloride )
Catalog No. M19813 CAS No. 554-92-7
Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 49 | In Stock |
|
| 100MG | 73 | In Stock |
|
| 200MG | 97 | In Stock |
|
| 500MG | 149 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTrimethobenzamide hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionTrimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
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DescriptionTrimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.(In Vitro):Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center.(In Vivo):The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration.
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In VitroTrimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center.
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In VivoThe oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration.
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SynonymsRo 2-9578 | Tribenzagan Hydrochloride
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorD2
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Research AreaOthers
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IndicationNausea and vomiting
Chemical Information
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CAS Number554-92-7
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Formula Weight424.92
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Molecular FormulaC21H29ClN2O5
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Purity>98% (HPLC)
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SolubilityDMSO:≥100 mg/mL (235.34 mM)
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SMILESCl.COc1cc(cc(OC)c1OC)C(=O)NCc1ccc(OCCN(C)C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Smith HS et al. Dopamine receptor antagonists. Ann Palliat Med. 2012 Jul;1(2):137-42.
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